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E2264. Imaging Findings In Neurosarcoidosis
Authors
  1. Ayah Megahed; Yale New Haven Health- Bridgeport Hospital
  2. Anas Bamashmos; Yale New Haven Health- Bridgeport Hospital
  3. Kareem El Fatairy; Yale New Haven Health- Bridgeport Hospital
  4. Ashkan Behzadi; Yale New Haven Health- Bridgeport Hospital
  5. Gaurav Parmar; Yale New Haven Health- Bridgeport Hospital
  6. Puneet Kochar; Penn State Hershey Medical Center
Background
Sarcoidosis is a systemic disease, of unknown etiology that can affect all parts of the body, typically the lungs and the lymph nodes. Histologically, there are characteristic non-caseating granulomas. Sarcoidosis can affect the head and spine, including the parenchyma, the nerve roots, the meningeal lining, and adjacent bones. Neurological involvement can be the presenting symptom in patients with sarcoidosis with systemic involvement. Signs and symptoms are non-specific and related to the site of granuloma formation.

Educational Goals / Teaching Points
• Discuss the pathology of sarcoidosis. • Discuss the imaging findings of neurosarcoidoisis in the brain. • Discuss the imaging findings of neurosarcoidosis in the orbit. • Discuss the imaging findings of neurosarcoidosis in the spine.

Key Anatomic/Physiologic Issues and Imaging Findings/Techniques
- Pathology of sarcoidosis and incidence of neurological involvement. -Manifestations of neurosarcoidosis in the brain: a) Leptomeningeal involvement b) Dural involvement c) Brain parenchymal involvement d) Hypothalamic involvement e) Pituitary involvement f) Skull involvement -Manifestations of neurosarcoidosis related to the cranial nerves. -Manifestations of neurosarcoidosis in the spine. a) Intramedullary involvement b) Leptomeningeal and dural involvement c) Bone involvement

Conclusion
Knowledge of the imaging features of sarcoidosis affecting the neurological system is paramount for diagnosis of central nervous system involvement in patients with known sarcoidosis, also, neurological symptoms may be the presenting symptoms in patients with unknown sarcoidosis.