Abstracts

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E1577. Vaping and E-Cigarette Associated Lung Injury: A Case-Based Review of Imaging Patterns of Disease
Authors
  1. Marlon Coelho; SUNY Upstate Medical University
  2. Atin Goel; SUNY Upstate Medical University
  3. Matthew Klumpp; SUNY Upstate Medical University
  4. Abtin Jafroodifar; SUNY Upstate Medical University
  5. Ernest Scalzetti; SUNY Upstate Medical University
Background
Electronic cigarette or vaping associated lung injury (EVALI) is an evolving pathology that has gained popularity in the medical community due to vastly increased use as an alternative to cigarette smoking. This has not proven to be without significant risk with a varied appearance of disease on lung imaging, most commonly presenting as acute lung injury in the form of organizing pneumonia or diffuse alveolar damage. The purpose of this abstract is to highlight the variety of imaging characteristics associated with EVALI at our institution. We intend to provide a case based review of imaging characteristics, discuss the pathophysiology based on current literature review and correlate these findings with patient presentations, pulmonary function, and overall patient outcomes.

Educational Goals / Teaching Points
To discuss the underlying mechanism and pathophysiology related to e-cigarette/vaping associated lung injury (EVALI). To describe the various imaging patterns of lung injury associated with e-cigarettes and vaping with a particular focus on high resolution computed tomography (HRCT). To provide a systematic approach to suspected cases of EVALI and a case-based review of the clinical and radiographic course of disease in confirmed cases. To correlate pathological results and physiological parameters (Pulmonary Function Tests) with imaging findings. To briefly summarize the clinical management and radiological follow-up of patients treated for EVALI. To provide appropriate differential diagnoses and/or overlapping imaging characteristics with other pathologies that do not meet criteria for diagnosis of EVALI.

Key Anatomic/Physiologic Issues and Imaging Findings/Techniques
To discuss the radiographic and high resolution computed tomography (HRCT) findings of EVALI. To highlight the pathology and patterns of lung disease in the setting of EVALI. To highlight the pathophysiology of the disease and present imaging characteristics at different patient acuities and outcomes. To discuss the imaging characteristics that all radiologists must be aware of and differential diagnoses based on clinical history.

Conclusion
EVALI is a complex medical condition related to e-cigarettes and vaping devices that have grown in popularity as an alternative to cigarette smoking. EVALI is associated with acute lung injury with the most common disease presentation as organizing pneumonia and diffuse alveolar damage. We intend to provide a case-based review depicting the various pathologic presentions of the disease and correlate these imaging findings directly with patient presentations, pulmonary function tests, and overall patient outcome.