E1572. Benign FDG Avid Lesions Seen on Oncologic PET/CT Imaging: A Review and Guide to Successfully Navigating These Potential Imaging Pitfalls
  1. Stephen Judge; NYU Winthrop Hospital
  2. Megan Le; NYU Winthrop Hospital
  3. Jason Hoffmann; NYU Winthrop Hospital
  4. Anca Kranz; NYU Winthrop Hospital
PET/CT is a relatively commonly obtained imaging study in the diagnosis, evaluation, and follow-up of a variety of cancers. However, as not all hyper metabolic foci on PET/CT represent malignancy, it is imperative for radiologists and trainees to understand this and be knowledgeable about both malignant and benign causes of hyper metabolism on PET/CT.

Educational Goals / Teaching Points
1. It is important for radiologists, nuclear medicine physicians, and trainees to be able to distinguish between physiological and non-physiological causes of F-18 fluorodeoxyglucose (FDG) avid foci, as well as to understand which are benign and which are malignant. 2. A working knowledge of common PET/CT imaging pitfalls is important for all trainees and radiologists so that they can maximize the value and impact of their interpretation of these studies.

Key Anatomic/Physiologic Issues and Imaging Findings/Techniques
This educational exhibit will review basic nuclear medicine physics of F-18 FDG PET/CT. It will detail physiologic and non-physiologic causes of update, including both benign and malignant etiologies, and highlight common and unique imaging pitfalls. The image rich exhibit will include (but not be limited to) topics of brown fat activation, endocrine causes such as the insulin effect, and systemic inflammatory disorders. We also discuss the potential impacts of misinterpretation of these potential pitfalls. The relevant literature on each of these topics will be reviewed.

Knowledge about and understanding of both benign and malignant causes of F-18 FDG focal uptake on PET/CT are essential for accurate image interpretation and optimal patient management.