Abstracts

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E1118. Literature and Case-Based Review of Adult and Pediatric Cystic Lung Disease
Authors
  1. Marlon Coelho; SUNY Upstate Medical University
  2. Atin Goel; SUNY Upstate Medical University
  3. Matthew Klumpp; SUNY Upstate Medical University
  4. Abtin Jafroodifar; SUNY Upstate Medical University
  5. Ernest Scalzetti; SUNY Upstate Medical University
Background
Cystic Lung Disease is a broad spectrum of heterogenous pathologies presenting with or associated with lung cysts as the primary finding on imaging. Pulmonary cysts are thin walled air filled lucencies interfaced within lung parenchyma, usually with a wall <2mm thick. Cysts may be primary or acquired/secondary to a range of multisystemic disease pathologies. High resolution computed tomography (HRCT) allows of accurate diagnosis of various pathologies associated with diffuse lung cyst formation and is a valuable tool for application in clinical medicine.

Educational Goals / Teaching Points
- To define cystic lung disease and the role of high resolution computed tomography (HRCT) in diagnosis. - To characterize pathologies related to adult and pediatric cystic lung disease and provide a case based review of pathologies related to neoplastic, congenital, infectious, and smoking related etiologies; and those associated with interstitial lung disease and multisystemic disease. - To distinguish imaging features on the basis of geographic distribution and underlying pathophysiology. - To device a comprehensive radiologic approach for cystic lung disease, allowing for confident diagnoses and highlight the overlapping features of disease pathology which require radio-pathological correlation. - To highlight the imaging characteristics of cystic lung disease on other diagnostic imaging modalities. - To discuss pathologies that mimic cystic lung disease on HRCT and which are often confused for or miscategorized as such.

Key Anatomic/Physiologic Issues and Imaging Findings/Techniques
- To review HRCT protocols in imagings cystic lung disease. - To discuss the differences in imaging adult and pediatric pathologies associated with cystic lung disease. - To discuss characteristic imaging patterns of each pathology and highlight the subtle differences in differential diagnoses. - To provide interpreting radiologists a template of key imaging features to aid in more accurate and clinically relevant reports.

Conclusion
Cystic lung disease encompasses a wide array of pathologies that can pose a diagnostic dilemma to radiologists and clinicians. Through this literature and case base review, our aim is to highlight image based characteristics of pathologies that can provide differential diagnoses of clinical relevance in the management of cystic lung disease. We aim to discuss both adult and pediatric cases of cystic lung disease in a single manuscript.