E5327. PSMA-RADS: A Primer for Radiologists
  1. Seyedeh Niloufar Rafiei Alavi; University of California, Irvine
  2. Shawn Sun; University of California, Irvine
  3. Vahid Yaghmai; University of California, Irvine
The PSMA Reporting and Data System (PSMA-RADS) was introduced to standardize reporting in prostate cancer imaging. Over the years, extensive research has validated the meaningfulness of its categories, such as the true positivity in PSMA-RADS 4 and 5 lesions, and high interobserver agreement has been demonstrated across a range of PSMA-directed radiotracers, even among less experienced readers. This system has proven valuable in complex clinical scenarios and aiding clinical decision-making. This review provides a case-based review of PSMA-RADS.

Educational Goals / Teaching Points
The primary educational objectives of this exhibit are to elucidate the intricacies of PSMA-RADS and its practical application in clinical practice. Attendees will gain a deeper understanding of the nuances of different PSMA-RADS categories and their significance in prostate cancer imaging. Moreover, the exhibit aims to enhance attendees' diagnostic skills by highlighting key pearls and pitfalls encountered when interpreting PSMA-RADS.

Key Anatomic/Physiologic Issues and Imaging Findings/Techniques
The PSMA-RADS reporting system conveys confidence in PCa presence and the need for further assessment, akin to BI-RADS. It is designed for lesions outside the prostate, complementing the MRI-based PI-RADS 2.0 system for prostate lesions. PSMA-RADS indicators apply to individual lesions or overall impressions of imaging studies, facilitating characterization.

PSMA-RADS empowers radiologists to accurately categorize lesions, facilitating precise patient management decisions. The high interobserver agreement across radiotracers and the utility of PSMA-RADS in complex clinical scenarios underscore its reliability.