E5324. Multisystem Imaging Manifestations of Fibromuscular Dysplasia
Authors
Anne Sailer;
Yale School of Medicine
Nadia Solomon;
Yale School of Medicine
Anne Marie Cahill;
Children's Hospital of Philadelphia
John Pellerito;
Zucker School of Medicine at Hofstra/Northwell Health System
Angelo Marino;
Yale School of Medicine
Douglas Katz;
New York University/Long Island School of Medicine
Margarita Revzin;
Yale School of Medicine
Background
Fibromuscular dysplasia (FMD) is an idiopathic segmentary, noninflammatory, nonatherosclerotic disease that can affect all layers of both small and medium-caliber arteries. Clinical manifestations are primarily dependent on the vessels affected by FMD, most frequently affecting the renal, carotid, and vertebral arteries. Complications of FMD can include severe stenosis, hypoperfusion, aneurysm, dissection, arterial occlusion, and subarachnoid hemorrhage in the brain.
Educational Goals / Teaching Points
1. Review pathophysiology of FMD and its multisystem potential complications and associated disorders. 2. Discuss general concepts of the assessment of the peripheral arterial system and aorta using Doppler US, CTA, and MRA, with emphasis on technique, protocol, and image optimization. 3. Demonstrate key multimodality imaging features FMD. Review role of various imaging applications in diagnosis and surveillance of FMD and its potential complications. 4. Discuss management options with review of available interventional radiology procedures. 5. Discuss the shared features and difference between FMD and polyarteritis nodosa, Takayasu, and other mimics.
Key Anatomic/Physiologic Issues and Imaging Findings/Techniques
1. Pathophysiology of FMD and mimics. 2. Multimodality imaging findings review: Doppler US, CTA, MRA. 3. Treatment, specifically focused on cutting balloons.
Conclusion
Knowledge of the imaging manifestations and treatment of FMD is essential for diagnosis and treatment of the underlying disease.
