E5281. Cervical, Celiac, and Sacral Ganglia Uptake: A Case-Based Pictorial Review of an Important Pitfall in Prostate Cancer PSMA PET Imaging
Authors
Janan Badier;
RUSH University Medical Center
Pokhraj Suthar;
RUSH University Medical Center
Sumeet Virmani;
RUSH University Medical Center
Background
PSMA PET imaging (68Ga or 18F) is now regarded as a game changer for staging and restaging of patients with confirmed high-risk prostate cancer or in patients with biochemical recurrence. Cervical, celiac, and sacral ganglia of the sympathetic trunk can show physiologic uptake mimicking nodal metastasis in PSMA PET imaging. These expected findings are considered an important pitfall that the interpreting physicians must be aware of.
Educational Goals / Teaching Points
In this pictorial review, we provide a case-based pictorial review of PSMA PET imaging (10 cases) showing various degree of PSMA avidity, characteristic locations, and configuration of the uptake patterns involving the cervical, celiac, and sacral ganglia.
Key Anatomic/Physiologic Issues and Imaging Findings/Techniques
We present a case-based pictorial review of PSMA PET imaging (10 cases) showing various degree of PSMA avidity involving the cervical, celiac, and sacral ganglia. The degree of uptake, anatomic location, and configuration help in differentiation of ganglia from adjacent lymph nodes.
Conclusion
This case-based educational exhibit raises awareness of this frequently encountered pitfall on PSMA PET imaging and strengthens the judgment of interpreting physicians.
