4550. Cohort Study of Low Dose Radiation Exposure and Radiation Damage in Interventional Radiology and Nuclear Medicine Workers
Authors* Denotes Presenting Author
Gang Liu *;
Gansu Provincial Center for Disease Control and Prevention
Objective:
To explore the basic scientific questions about the health effects of radiation and provide direct data support for radiobiological knowledge and epidemiological findings.
Materials and Methods:
From 2010 to 2021, a cohort of 1827 radiologists, including 1216 general radiologists, 551 interventional radiologists, and 60 nuclear medicine practitioners, was established in accordance with the work programmer for a cohort study of radiological staff in medical institutions. We aimed to study the dose-response relationship between exposure dose and occupational health examination results.
Results:
The mean annual dose for interventional radiology group, nuclear medicine, and general radiology group was 0.86 ± 0.25, 0.44 ± 0.11, 0.37 ± 0.09 ×10-3 Sv, respectively. The detection rate of micronucleus, the chromosomal aberration rate, the detection rate of opacification in posterior pole subcapsular lens and the cancer detection rate in interventional radiology group and nuclear medicine group was higher than that in general radiation. The difference between the detection rate of micronucleus in the interventional radiology group and the general radiology group was statistically significant.
Conclusion:
In this study, we found that low doses of radiation can cause radiation damage to radiation workers to a certain extent, especially those engaged in interventional radiology and nuclear medicine. It is suggested that chromosome aberration analysis is an important index for occupational health monitoring of radiologists. Although the findings suggest an improvement in cancer detection rates, the carcinogenic effects of low doses need further study.
