E2828. Case-Based Review of Papillary Carcinoma of the Breast
  1. Hannah Olson; University of Missouri–Kansas City
  2. Amy Patel; Liberty Hospital Department of Radiology; University of Missouri–Kansas City
Papillary carcinoma of the breast is a ductal malignancy which comprises 1 - 2% of breast cancers. Papillary neoplasia is a spectrum from benign papilloma, EPC, to invasive papillary carcinoma. Invasive papillary carcinomas classically present with nipple discharge and are most commonly seen in postmenopausal females. Papillary carcinomas can be within the duct and classified as papillary ductal carcinoma in situ, associated with a cystic component (classified as an intracystic papillary carcinoma), or without a cyst (classified as solid papillary carcinoma).

Educational Goals / Teaching Points
This exhibit will review the imaging findings of papillary carcinomas of the breast by describing imaging from recent cases of biopsy-proven papillary carcinoma detected at our institution.

Key Anatomic/Physiologic Issues and Imaging Findings/Techniques
Papillary carcinoma of the breast most commonly appears as a round, oval, or lobulated mass with circumscribed margins on mammography. Microcalcifications or dilated ducts may or may not be present. On ultrasound, papillary carcinomas appear as hypoechoic, solid masses, with posterior acoustic enhancement. Papillary carcinomas demonstrate high signal intensity on T-2 weighted images and varying signal intensities on T-1 weighted images as serous or hemorrhagic components are common. Papillary neoplasms can be in situ or invasive.

The purpose of this educational exhibit is to review papillary carcinoma of the breast with an emphasis on the key imaging features.