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Background
A myriad of classic radiological signs has been described in the literature across imaging modalities. Most of these signs are associated with a particular diagnosis and are pathognomonic, but they can also be related to normal anatomical variants. For simplification, a majority of imaging signs are named after common day-to-day objects like the cottage loaf or the water lily signs. Knowledge of such signs can help the radiologists to quickly come to a particular diagnosis. Here, we provide a pictorial review of various classic signs of hepatobiliary radiology with review of imaging appearance and clinical relevance.

Educational Goals / Teaching Points
Normal variants in liver anatomy such as Beaver tail liver. Examples of several hepatobiliary radiological signs, with the different hepatobiliary pathologies. Pathophysiology, appearance, clinical relevance, and differential diagnosis of the radiologic signs and diseases will be discussed.

Key Anatomic/Physiologic Issues and Imaging Findings/Techniques
Atoll sign, bright dot sign, cluster sign, cottage leaf sign, double target sign, focal hepatic hot spot sign, light bulb sign, doughnut sign, lollipop sign, nodule in nodule appearance, nutmeg liver, periportal halo sign, reverse target sign, Right posterior hepatic notch sign, expanded gall bladder fossa sign, snake/serpent sign, sonographic halo sign, starry sky appearance (USG), turtleback sign, water lily sign, wheels within wheels sign, spoke wheel sign, interface sign, hellmer’s sign, white liver sign, scalloping sign, patent track sign, chilaiditi sign, flip-flop sign, lucent liver sign, corkscrew hepatic arteries.

Conclusion
This exhibit will review and describe some classic radiological signs associated with hepatic and biliary pathologies and will discuss their underlying pathophysiology, clinical relevance, and differential diagnosis.