E2769. Ga-68 DOTATATE PET/CT Evaluation of Extra Gastro-Entero-Pancreatic Neuroendocrine Tumors: Spectrum of Case-Based Multimodality Review
Authors
Pokhraj Suthar;
Rush University Medical Center
Sumeet Virmani;
Rush University Medical Center
Background
Gallium-68 DOTATATE PET/CT is now considered the gold standard for imaging neuroendocrine tumors. Recent availability of this positron-emitting radio-labeled somatostatin analogue has a huge impact in the diagnosis, staging, and surveillance of patients with extra gastro-entero-pancreatic neuroendocrine tumors.
Educational Goals / Teaching Points
The purpose of this case-based pictorial exhibit is to highlight imaging spectrum of various findings, including normal physiological distribution and variation, benign, incidental and pathologic abnormalities, multimodality comparison and its superiority over conventional CT/MR and octreotide imaging when available, Gallium-68 DOTATATE PET CT impact over patient management in extra gastro-entero-pancreatic neuroendocrine tumors.
Key Anatomic/Physiologic Issues and Imaging Findings/Techniques
We present a case-based multimodality pictorial review (Gallium-68 DOTATATE PET-CT, CT, and MRI) highlighting the spectrum of 20 cases of extra gastro-entero-pancreatic neuroendocrine tumors, including adrenal paraganglioma (pneochromocytoma), extra adrenal paraganglioma (carotid body, jugulotympanic, glomus vagale, organ of Zuckerkandl, bladder base, intracardiac), lung carcinoid, thymic neuroendocrine tumors, phosphaturic mesenchymal tumors, and medullary thyroid tumor and others.
Conclusion
Gallium-68 DOTATATE PET/CT is the new gold standard for neuroendocrine tumor diagnosis and has a huge impact on patient management. The presented PET-CT pictorial review with multimodality correlation raises awareness and strengthens the judgment of the reading physician for extra gastro-entero-pancreatic neuroendocrine tumors.
