E2648. A Wolf in Sheep's Clothing: Malignant Mimickers of Benignity in Genitourinary Imaging
  1. Antonia Gurney; University of Nebraska Medical Center
  2. Elizabeth Edney; University of Nebraska Medical Center
  3. Ryan Downey; University of Nebraska Medical Center
A myriad of malignant lesions of the genitourinary system can masquerade as common benign findings on CT and MRI. Consequently, the radiologist must be aware of these potential pitfalls so that malignancy does not go undiagnosed, and patients can receive appropriate treatment.

Educational Goals / Teaching Points
This educational exhibit will review malignant lesions which may simulate benignity by location: renal, adrenal, bladder, urinary tract, retroperitoneum, and reproductive organs. The specific imaging features which should raise suspicion for underlying malignancy rather than a nonneoplastic process will be emphasized. Additionally, clinical situations which may suggest a malignant etiology for a particular patient presentation will be described. Situations when biopsy or surgical excision are necessary to make a definitive diagnosis will be reviewed.

Key Anatomic/Physiologic Issues and Imaging Findings/Techniques
Representative examples of malignant lesions simulating benign lesions on CT and MRI will be shown. Subtle but critical differentiating imaging features and clinical presentations of malignant from benign lesions will be emphasized. Situations when biopsy or surgical excision are ultimately necessary for definitive diagnosis will also be discussed.

A number of malignancies involving the genitourinary system can simulate benign disease. Familiarity with the spectrum of malignant processes masquerading as benign lesions is crucial to make the correct diagnosis and ensure proper patient care.