ARRS 2022 Abstracts

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E2117. All “I’s” on the IRB: The Imagers’ Interactive Instruction on the Institutional Review Board
Authors
  1. Karoly Viragh; Olive View-UCLA Medical Center
  2. Mariam Thomas; Olive View-UCLA Medical Center
Background
All radiologists will encounter an IRB directly or indirectly in the course of their careers. The purpose of the educational exhibit is to demystify the IRB for radiology trainees and interested professionals by authors who are members of an IRB.

Educational Goals / Teaching Points
The goals of this exhibit are to review the definition and structure of an IRB; review the ethical and historical motivation for establishing IRBs with landmark regulations/reports; and illustrate/explain the updated current federal regulations. We present multiple carefully chosen practical scenarios that radiology trainees and professionals may encounter based on our IRB experience, with pearls and pitfalls.

Key Anatomic/Physiologic Issues and Imaging Findings/Techniques
IRBs were established to review and approve all research involving human subjects based on historically established ethical principles to minimize risk and maximize benefit. There are well-defined categories that pose no or minimal risk and do not require formal review; however, all human trials with any considerable risk to the research subjects requires full IRB review. Numerous radiology-relevant practical scenarios are included for illustration.

Conclusion
All radiologists should be familiar with IRBs to understand their structure and role in overseeing the clinical studies that comprise the fundamentals of evidence-based practice.