ARRS 2022 Abstracts


E1184. A Review of Benign and Malignant Fibrous Soft Tissue Tumors in Adults
  1. Jonathan Lin; UCLA Health System
  2. Benjamin Levine; UCLA Health System
  3. Kambiz Motamedi; UCLA Health System
Fibrous soft tissue tumors represent a diverse group of lesions with pathologic entities histologically composed of fibrous connective tissue. These lesions range from benign proliferations to locally aggressive and malignant tumors. Fibrous lesions can occur in numerous anatomic locations. Furthermore, the MRI characteristics can vary, depending on a lesion’s histologic composition.

Educational Goals / Teaching Points
The purpose of this review is to provide an overview of the most common benign and malignant fibrous tumors in adults. Major categories of fibroblastic and myofibroblastic lesions along with their clinical presentation, imaging findings, and differential diagnoses will be discussed. This educational exhibit is targeted towards radiology trainees, general radiologists, and musculoskeletal (MSK) radiologists.

Key Anatomic/Physiologic Issues and Imaging Findings/Techniques
In adults, fibrous soft tissue tumors can be broadly classified as benign fibrous proliferations, fibromatoses, and fibrous sarcomas. Benign fibrous proliferations and superficial fibromatoses are generally thought to result from a reactive process. Deep fibromatoses are locally aggressive lesions and have a high rate of recurrence. Fibrous sarcomas can appear non-specific and can be difficult to exclude without tissue biopsy. MRI is the imaging modality of choice for the evaluation of a suspected fibrous soft tissue tumor, because it can help to not only confirm the diagnosis of a tumor but also assess local extent of disease.

Fibrous soft tissue tumors encompass numerous benign and malignant lesions and can be challenging to accurately diagnose. Understanding the key imaging features and clinical behavior of common fibrous lesions is critical to confirm the suspected diagnosis and guide clinical management.