ARRS 2022 Abstracts

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1424. Portable Low-Field MRI: Scanning Experience in the Neonatal Intensive Care Unit
Authors * Denotes Presenting Author
  1. Maura Sien *; Children's Mercy Kansas City
  2. Amie Robinson; Children's Mercy Kansas City
  3. Nathan Artz; Children's Mercy Kansas City
  4. Christopher Nitkin; Children's Mercy Kansas City
  5. Ara Hall; Children's Mercy Kansas City
  6. Marcie Files; Children's Mercy Kansas City
  7. Sherwin Chan; Children's Mercy Kansas City
Objective:
High-field MRI (HF-MRI) (=1T) is the workhorse of pediatric neuroimaging. Hyperfine (Guilford, CT) recently introduced an FDA 510k cleared low-field MRI (LF-MRI) (0.064T) system that is portable and can be used in various patient environments without the need for specialty MRI conditional equipment. Our aim was to assess the feasibility and technical capability of using this LF-MRI to scan infants at their bedside in the neonatal intensive care unit (NICU).

Materials and Methods:
This was a single-site prospective cohort study in pediatric patients aged =4 months and weighing =2 kg between October and December 2020. Subjects who underwent standard of care (SOC) head imaging in our Neonatal Intensive Care Unit (NICU) were approached for consent. Consented subjects underwent LF-MRI at the patient’s bedside in the NICU within 24-hrs of SOC imaging. All SOC equipment, such as patient crib, ventilator, monitors, computers, and vital leads remained on the subject and adjacent to the bedside during the scan. All subjects were swaddled, and no additional sedation was given. All LF-MRI scans included T1, T2, FLAIR, and DWI sequences. The total exam time for LF-MRI was 35 minutes. We measured the rate of successful exam completion, defined as including all four sequences without substantial artifact.

Results:
Fourteen subjects were enrolled, and 17 exams were performed. Three subjects underwent two LF-MRI exams. Of the 17 exams, 94% (16/17) were successfully completed. One subject’s exam was terminated due to subject movement. The subject’s SOC bedside configuration and equipment did not have to be modified to complete any scans. Subjects had an average age of 27.9 (Range 1-122) days and were split evenly between genders (females: n=7). Subjects had underlying clinical diagnoses of intraventricular hemorrhage (n=5), hypoxic ischemic encephalopathy (n=5), myelomeningocele (n=2), seizures (n=1), or spinal cord compression (n=1).

Conclusion:
Portable LF-MRI was successfully used to scan subjects at their bedside in the NICU without modifying the clinical setup of the subject’s room or SOC medical monitoring devices. Overall, this technology warrants further research efforts to determine its full capabilities and application.